BPC 157 (Lub Cev Tiv Thaiv Lub Cev -157) yog ib qho ruaj khov pentadecapeptide- muaj 15 amino acids- uas tshwm sim hauv tib neeg lub plab zom mov. Thawj zaug cais thiab txheeb xyuas xyoo 1993 los ntawm pab pawg tshawb fawb Croatian los ntawm kev tiv thaiv cov proteins pom hauv cov kua hauv plab, nws feem ntau hu ua "Wolverine Peptide." Tam sim no, nws yog ib qho ntawm cov ntsiab lus tseem ceeb ntawm kev tshawb fawb hauv thaj chaw biomedicine thiab peptide science; nws cov txiaj ntsig tseem ceeb nyob hauv thaj chaw xws li cytoprotection thiab kho cov ntaub so ntswg, muaj peev xwm tseem ceeb rau kev tshawb fawb tshawb fawb thiab kev siv tswv yim.
Qhov zoo ntawm BPC 157
Hais txog nws cov yam ntxwv tseem ceeb, qhov zoo tshaj plaws ntawm BPC 157 yog nws txoj kev ruaj ntseg thiab kev ua haujlwm ntau yam. Nws tseem nyob ruaj khov nyob rau hauv ib puag ncig acidic ntawm tib neeg lub plab rau ntau tshaj 24 teev thiab tiv taus cov enzymatic degradation-ib qho tshwj xeeb uas txawv nws ntawm feem ntau ntawm peptides, uas feem ntau ua rau tawg sai. Nws cov txheej txheem tseem ceeb ntawm kev ua haujlwm ntawm cytoprotection; Nws ua tiav qhov no los ntawm bidirectionally modulating nitric oxide (NO) system tswj vascular thiab cellular homeostasis. Raws li qhov tshwm sim, nws qhib cov kev taw qhia txoj hauv kev- xws li FAK-paxillin txoj hauv kev- los txhawb kev txav chaw ntawm tes, adhesion, thiab ciaj sia taus, thaum tseem txhawb nqa kev qhia ntawm Vascular Endothelial Growth Factor (VEGF) kom nrawm angiogenesis. Tsis tas li ntawd, nws txo cov qib ntawm cov kab mob cytokines{10}}xws li IL-6 thiab TNF- - yog li tsim kom muaj ib puag ncig zoo rau cov ntaub so ntswg kho.
Lub peev xwm ntawm BPC 157
Lub peev xwm ntawm BPC 157 feem ntau yog nyob rau ntawm peb qhov tseem ceeb. Ua ntej yog kev kho cov ntaub so ntswg: nws ua kom nrawm ntawm kev kho cov nqaij mos raug mob- xws li cov uas cuam tshuam rau ntawm daim tawv nqaij, cov leeg, cov leeg, thiab ligaments- ib txhij ua kom muaj zog biomechanical ntawm cov chaw raug mob. Tsis tas li ntawd, nws muaj txiaj ntsig zoo rau kev kho cov pob txha pob txha, pob txha raug mob, thiab visceral anastomoses; yog li ntawd, nws tau txais kev saib xyuas ntau nyob rau hauv kev ua kis las kho mob thiab kho mob. Qhov thib ob yog kev tiv thaiv lub cev: nws tiv thaiv lub plab hnyuv mucosa, tiv thaiv lub plab epithelium tiv thaiv kev puas tsuaj los ntawm cov neeg ua haujlwm xws li cawv thiab tsis yog -steroidal anti- tshuaj tiv thaiv kab mob (NSAIDs). Tsis tas li ntawd, nws muab cov txiaj ntsig kev tiv thaiv rau ntau yam kabmob -xws li lub plawv, daim siab, thiab lub hlwb- thiab tau pom muaj peev xwm tseem ceeb hauv kev tshawb fawb txog cov xwm txheej xws li mob plab ulcerative thiab ischemia - raug mob reperfusion. Qhov thib peb yog hais txog "los ntshav-thrombosis paradox": txawm hais tias nws tsis cuam tshuam ncaj qha rau cov coagulation cascade, nws ua rau muaj kev tswj hwm kev tswj hwm ntawm ob qho tib si los ntshav thiab thrombosis- ua yeeb yam los tawm tsam los ntshav los ntawm cov tshuaj tiv thaiv coagulant thaum tib lub sijhawm ntawm cov ntshav txhaws.
Lub luag haujlwm ntawm BPC 157
Nws lub zog tseem ceeb ncaj qha hais txog qhov mob tseem ceeb: nws ua kom lub cellular kho cov teeb liab txoj hauv kev txhawm rau txhawm rau angiogenesis- yog li xa cov khoom noj tseem ceeb rau cov chaw raug mob-thaum ib txhij tswj cov inflammatory cytokine qib kom sai sai txo qhov o thiab mob, ua rau lub sijhawm rov qab los sai. Txawm hais tias qhov teeb meem yog leeg lossis cov leeg mob hauv cov neeg nyiam kev noj qab haus huv, mob nqaij mos raug mob hauv cov neeg ncaws pob, lossis mob plab hnyuv thiab mucosal puas tsuaj rau cov pej xeem, BPC 157 muab cov phiaj xwm kho mob thiab meej. Nws accelerates kho cov ntaub so ntswg xws li daim tawv nqaij, ligaments, thiab pob txha, txhim kho cov neeg kho tshuab lub zog ntawm cov chaw raug mob; Nyob rau tib lub sijhawm, nws tiv thaiv lub plab hnyuv mucosa tiv thaiv kev puas tsuaj los ntawm cawv thiab tshuaj, thiab muaj kev tswj xyuas ob txoj kev los ntshav thiab thrombosis- daws cov teeb meem kev kho mob uas cuam tshuam nrog kev kho cov ntaub so ntswg.
BPC 157 boasts lub qhov rais tshwj xeeb kev nyab xeeb; nws tsis muaj qhov cuam tshuam loj heev, yog qhov zoo - zam, thiab tsis muaj qhov cuam tshuam tseem ceeb. Tsis tas li ntawd, nws ua tau raws li cov qauv purity nruj thiab raug tswj xyuas nruj heev.
Hais goodbye rau lub sij hawm rov qab mus ntev thiab xaus rau kev raug mob rov qab! Siv lub zog ntawm kev tshawb fawb, BPC 157 txhawb nqa koj lub cev cov txheej txheem kho ntuj. Ntau yam txaus kom ua tau raws li qhov xav tau ntau yam -los ntawm kev tshaj tawm- kev tawm dag zog rov qab thiab kho kev puas tsuaj rau kev tu lub cev txhua hnub- nws ua haujlwm raws li koj tus khub txhim khu kev qha, siv zog ua kom koj lub cev tsis muaj zog ntawm tus kheej - kho lub peev xwm los tiv thaiv txhua nti ntawm koj txoj kev noj qab haus huv.